Palabra clave:

Palabra clave:

Descripción: “...In contrast, for higher flow rates consistent with clinical infusions, the radius of the infusion catheter had minimal effect on the distribution of the infused drug, with most being transported into the tissue around the shaft of the catheter.Resumen ─ Convection-enhanced delivery es una técnica que permite transportar drogas directamente en el cerebro para el tratamiento de enfermedades del sistema nervioso central. ...”

Descripción: “...Due to these anomalies, the drug that initially was effective for the treatment of aforementioned disease, may not be administered in the required amount, at the right time and the expected location for effective treatment. ...”

Descripción: “...The sexual activity index decreased after  administration of 1.5 and 2.0 mg kg-1 picrotoxin. The inhibitory effects of the larger doses of picrotoxin on male sexual behavior may be a consequence of both a drug interference with motor function and a dose-dependent picrotoxin-induced stress influence.Key words: GABA, male sexual behavior, picrotoxin, sexual stimulation, sexual inhibition.RESUMEN: Fueron evaluados los efectos de varias dosis de picrotoxina sobre el comportamiento sexual de ratas macho. ...”

Palabra clave: “...Secondary effect...”

Palabra clave: “...aseptic meningitis induced by drugs...”

Descripción: “...In addition, in the case that Leishmania proteins have its tridimensional structure reported, docking analysis were simulated to corroborate interaction with the drug. At the end, a selection of 10 drugs was identified and is currently being evaluated in in vitro test. ...”